Rounds illness scripts.
Patterns you can recognize.
Classic presentations, workup, mechanism, management, and clinical pivots—free to browse for Step 1 and clerkships.
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85 conditions, A–Z
85 scripts · search every field
A
17- ACE Inhibitor-Induced Acute Kidney Injury in Bilateral Renal Artery StenosisPrecipitous GFR drop occurring when ACEi/ARB removes the angiotensin II-mediated efferent arteriolar tone that sustains filtration pressure in bilateral RAS.Read
- Acute AppendicitisAcute inflammation of the vermiform appendix, most commonly from luminal obstruction, causing right lower quadrant pain and peritoneal signs.Read
- Acute CholecystitisAcute gallbladder wall inflammation, usually from cystic duct obstruction by a gallstone, causing RUQ pain, fever, and leukocytosis.Read
- Acute Compartment SyndromeElevated pressure within a closed fascial compartment compromises perfusion, causing ischemia and irreversible muscle/nerve damage if untreated.Read
- Acute Decompensated Heart FailureSudden worsening of HF symptoms causing fluid overload and/or low cardiac output requiring urgent hospitalization.Read
- Acute Kidney InjuryAbrupt decline in renal function (↑Cr ≥0.3 mg/dL in 48h or ≥1.5× baseline in 7d) causing azotemia and fluid/electrolyte dysregulation.Read
- Acute PancreatitisAcute inflammation of the pancreas due to premature activation of digestive enzymes, causing autodigestion and systemic inflammation.Read
- AdenomyosisEctopic endometrial glands/stroma within the myometrium, causing a diffusely enlarged, boggy, tender uterus.Read
- Adrenal (Addisonian) CrisisLife-threatening acute glucocorticoid (± mineralocorticoid) deficiency causing hemodynamic collapse, typically precipitated by physiologic stress.Read
- Alcohol WithdrawalCNS hyperexcitability syndrome following abrupt cessation or reduction of chronic heavy alcohol use, ranging from tremor to life-threatening seizures and delirium.Read
- AlkaptonuriaAutosomal recessive deficiency of homogentisate 1,2-dioxygenase causing homogentisic acid accumulation, ochronosis, and progressive arthropathy.Read
- Alport SyndromeHereditary nephritis caused by type IV collagen gene mutations (COL4A3/A4/A5) disrupting the glomerular basement membrane, cochlea, and lens.Read
- AnaphylaxisLife-threatening systemic hypersensitivity reaction causing distributive shock via massive mast cell/basophil mediator release.Read
- Aortic DissectionTear in aortic intima allows blood to enter and split the media, creating a false lumen; classified Type A (ascending) vs Type B (descending).Read
- Asthma ExacerbationAcute worsening of reversible airflow obstruction from bronchospasm, mucosal edema, and mucus plugging in a known or new asthmatic.Read
- Atrial FibrillationChaotic, disorganized atrial electrical activity causing irregularly irregular rhythm and loss of coordinated atrial contraction.Read
- Atrial Septal DefectCongenital opening in the interatrial septum causing left-to-right shunting, right heart volume overload, and increased pulmonary blood flow.Read
B
2C
4- Carcinoid SyndromeParaneoplastic syndrome from serotonin-secreting well-differentiated neuroendocrine tumors (NETs) that have metastasized to the liver, bypassing hepatic degradation.Read
- CellulitisAcute bacterial infection of the deep dermis and subcutaneous fat, most often caused by Streptococcus pyogenes or Staphylococcus aureus.Read
- Community-Acquired PneumoniaAcute lower respiratory tract infection acquired outside hospital, causing alveolar consolidation and impaired gas exchange.Read
- COPD ExacerbationAcute worsening of COPD symptoms beyond normal day-to-day variation, typically triggered by infection or environmental irritants.Read
D
3- Deep Vein ThrombosisThrombus formation in a deep vein (most often proximal lower extremity) causing obstruction and risk of pulmonary embolism.Read
- Dependent Personality DisorderCluster C personality disorder with pervasive, excessive need to be cared for, driving submissive, clinging behavior and intense fear of abandonment.Read
- Diabetic KetoacidosisLife-threatening triad of hyperglycemia, anion-gap metabolic acidosis, and ketonemia due to absolute insulin deficiency.Read
E
2- Ectopic PregnancyImplantation of a fertilized ovum outside the uterine cavity, most commonly in the fallopian tube (~95%).Read
- EpiglottitisAcute, life-threatening supraglottic inflammation causing rapid airway obstruction; classically Haemophilus influenzae type b in children, now more common in adults.Read
F
2- Fibromuscular DysplasiaNon-inflammatory, non-atherosclerotic disease of medium-sized arteries causing stenosis, aneurysm, and dissection, most often in renal and carotid arteries.Read
- Fluoroquinolone Adverse EffectsBroad-spectrum antibiotics (ciprofloxacin, levofloxacin, moxifloxacin) with a distinctive toxicity profile spanning tendons, CNS, cardiac conduction, and glucose regulation.Read
G
5- Giant Cell ArteritisLarge-vessel granulomatous vasculitis of the aorta and its branches, classically affecting the temporal artery in patients >50.Read
- Glanzmann ThrombastheniaAutosomal recessive deficiency/dysfunction of platelet GPIIb/IIIa (αIIbβ3) causing failure of platelet aggregation despite normal platelet count.Read
- GoutMonosodium urate crystal deposition in joints causing recurrent episodes of severe acute inflammatory arthritis, typically monoarticular.Read
- Greater Trochanteric Pain SyndromeLateral hip pain arising from gluteal tendinopathy and/or trochanteric bursitis at the greater trochanter, formerly called trochanteric bursitis.Read
- Guillain-Barré SyndromeAcute post-infectious autoimmune demyelinating polyradiculoneuropathy causing ascending flaccid paralysis, areflexia, and potential respiratory failure.Read
H
3- Hartnup DiseaseAutosomal recessive defect in neutral amino acid transport (SLC6A19) causing tryptophan malabsorption and pellagra-like syndrome.Read
- HyperkalemiaSerum potassium >5.5 mEq/L causing life-threatening cardiac and neuromuscular dysfunction via altered membrane potential.Read
- Hyperosmolar Hyperglycemic StateLife-threatening diabetic emergency with extreme hyperglycemia, profound dehydration, and hyperosmolality WITHOUT significant ketoacidosis.Read
I
5- IgA Vasculitis (Henoch-Schönlein Purpura)Small-vessel IgA-mediated leukocytoclastic vasculitis causing the classic tetrad of palpable purpura, arthritis, abdominal pain, and renal disease.Read
- Infective EndocarditisMicrobial infection of native or prosthetic heart valves producing vegetations, bacteremia, and systemic embolic phenomena.Read
- IntussusceptionTelescoping of a proximal bowel segment into a distal one, causing obstruction and ischemia; most common in infants 6–36 months.Read
- Iron Deficiency AnemiaMost common anemia worldwide; caused by depleted iron stores leading to impaired hemoglobin synthesis and microcytic, hypochromic RBCs.Read
- Ischemic StrokeSudden focal neurologic deficit from arterial occlusion causing cerebral infarction; accounts for ~87% of all strokes.Read
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1M
3- Major Depressive DisorderMood disorder characterized by ≥2 weeks of depressed mood and/or anhedonia plus ≥4 additional neurovegetative symptoms causing functional impairment.Read
- Miller Fisher SyndromeAutoimmune GBS variant characterized by the classic triad of ophthalmoplegia, ataxia, and areflexia following a preceding infection.Read
- Myocardial InfarctionIrreversible myocardial ischemia causing cardiomyocyte necrosis, most often from acute coronary artery occlusion by thrombus on ruptured atherosclerotic plaque.Read
N
4- Necrotizing FasciitisRapidly spreading bacterial infection of the deep fascia causing tissue necrosis, systemic toxicity, and high mortality if not surgically debrided emergently.Read
- NephrolithiasisCrystalline stone formation in the urinary tract causing obstruction, colicky flank pain, and hematuria.Read
- Nephrotic SyndromeGlomerular disease causing massive proteinuria (>3.5 g/day) with hypoalbuminemia, edema, and hyperlipidemia/lipiduria.Read
- Neuroleptic malignant syndromeLife-threatening hyperdopaminergic blockade reaction to antipsychotics causing hyperthermia, rigidity, autonomic instability, and altered mental status.Read
O
2- OsteomyelitisInfection of bone, most commonly bacterial, causing bone destruction and marrow inflammation; classified as hematogenous, contiguous, or vascular insufficiency.Read
- Ovarian TorsionTwisting of the ovary (and often fallopian tube) on its ligamentous supports, compromising blood flow and causing ischemia.Read
P
9- Paranoid Personality DisorderCluster A personality disorder characterized by a pervasive, enduring pattern of unwarranted distrust and suspiciousness of others' motives.Read
- Pelvic Inflammatory DiseaseAscending polymicrobial infection of the upper female genital tract (uterus, tubes, ovaries), most often sexually transmitted.Read
- PheochromocytomaCatecholamine-secreting tumor of adrenal medulla chromaffin cells causing episodic or sustained hypertension and sympathetic surges.Read
- Placental AbruptionPremature separation of a normally implanted placenta from the uterine wall before delivery, causing hemorrhage and fetal compromise.Read
- Preeclampsia with Severe FeaturesHypertensive disorder of pregnancy ≥20 weeks with end-organ damage (BP ≥160/110, proteinuria ± severe features).Read
- Primary Hyperaldosteronism (Conn Syndrome)Autonomous adrenal aldosterone overproduction causing resistant hypertension, hypokalemia, and metabolic alkalosis with suppressed renin.Read
- Pseudomembranous ColitisC. difficile toxin-mediated colitis causing pseudomembrane formation on colonic mucosa, classically following antibiotic use.Read
- Pulmonary EmbolismAcute obstruction of pulmonary arterial circulation, most often by thrombus from deep veins, causing hypoxia and right heart strain.Read
- Pyloric StenosisHypertrophy of the pyloric muscle causing progressive gastric outlet obstruction in infants, typically 2–8 weeks of age.Read
S
12- Seborrheic DermatitisChronic, relapsing inflammatory skin condition causing greasy, yellowish scales and erythema in sebaceous gland-rich areas.Read
- Secondary SyphilisSystemic dissemination of Treponema pallidum 4–10 weeks after primary infection, classically causing a diffuse rash including palms and soles.Read
- SepsisLife-threatening organ dysfunction caused by a dysregulated host response to infection (SOFA ≥2 change from baseline).Read
- Septic ArthritisBacterial infection of a synovial joint causing acute inflammation; a surgical emergency requiring urgent drainage to prevent joint destruction.Read
- Serotonin SyndromeLife-threatening excess serotonergic activity at CNS/PNS receptors, classically from drug combination, causing neuromuscular, autonomic, and mental status changes.Read
- Sickle Cell Vaso-Occlusive CrisisAcute pain crisis in sickle cell disease caused by sickling of RBCs occluding microvasculature, causing ischemia and infarction.Read
- Small Bowel ObstructionMechanical blockage of small intestinal lumen causing failure of distal passage of contents, most commonly from adhesions.Read
- Status EpilepticusSeizure lasting ≥5 minutes OR ≥2 seizures without return to baseline consciousness between them.Read
- Stevens-Johnson SyndromeSevere mucocutaneous hypersensitivity reaction with epidermal detachment involving <10% BSA, caused by drugs or infections.Read
- Subarachnoid HemorrhageBleeding into the subarachnoid space, most often from a ruptured intracranial aneurysm, causing sudden severe headache.Read
- Systemic Lupus ErythematosusSystemic autoimmune disease causing multi-organ inflammation via autoantibodies and immune complex deposition, with relapsing-remitting course.Read
- Systemic Lupus Erythematosus (SLE)Chronic autoimmune disease with multi-organ involvement driven by loss of tolerance to nuclear antigens and immune complex deposition.Read
T
4- Takotsubo CardiomyopathyTransient, reversible apical LV ballooning triggered by acute emotional or physical stress, mimicking ACS without obstructive coronary disease.Read
- Tension PneumothoraxAir trapped under pressure in the pleural space causing mediastinal shift, obstructive shock, and cardiorespiratory collapse.Read
- Thyroid StormLife-threatening hypermetabolic crisis from extreme thyroid hormone excess, typically precipitated by physiologic stress in undertreated hyperthyroidism.Read
- Tumor Lysis SyndromeMetabolic emergency from massive tumor cell lysis releasing intracellular contents, causing hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia.Read
U
1V
3- VaricoceleAbnormal dilation of the pampiniform venous plexus within the spermatic cord, most common cause of correctable male infertility.Read
- Vitamin B6 (Pyridoxine) DeficiencyDeficiency of pyridoxine, a PLP-dependent cofactor for neurotransmitter synthesis and transamination, causing neuropathy, dermatitis, and sideroblastic anemia.Read
- Vitamin E DeficiencyFat-soluble antioxidant deficiency causing progressive spinocerebellar ataxia and peripheral neuropathy, most often from fat malabsorption.Read
W
2- Wilson's DiseaseAutosomal recessive ATP7B mutation causing defective hepatic copper excretion, leading to toxic copper accumulation in liver, brain, and eyes.Read
- Wolff-Parkinson-White SyndromePre-excitation syndrome caused by an accessory pathway (Bundle of Kent) bypassing the AV node, producing a characteristic ECG triad and predisposing to life-threatening tachyarrhythmias.Read
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Educational use only. Study frameworks for medical students—not medical advice. Follow your institution's protocols and current guidelines at the bedside.